Progeria is a disease that produces rapid aging, beginning in childhood.
Progeria is a rare condition that is remarkable because its symptoms strongly resemble normal human aging, but occur in young children.
Ninety percent of children with progeria have a mutation on the gene that encodes the protein lamin A. Progeria usually occurs without cause. It is only very rarely seen in more than one child in a family.
The signs include:
Cardiac stress testing may reveal signs of early atherosclerosis of blood vessels.
Genetic testing can detect mutations in lamin A that cause progeria.
There is presently no treatment for progeria.
Progeria Research Foundation, Inc. -- www.progeriaresearch.org
Progeria is associated with a short lifespan. The average patient survives to the early teens. However, some patients can live up to 30 years. The cause of death is usually related to the heart or a stroke as a result of the progressive atherosclerosis.
Call for an appointment with your health care provider if you child does not appear to be growing or developing normally.
There is no known prevention.